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Sanofi, GSK variant-specific COVID shot found effective against Omicron

By Natalie Grover PARIS/LONDON (Reuters) - Late-stage data on an experimental COVID-19 vaccine from Sanofi (NASDAQ:SNY) and GSK has showed the shot confers protection against...
Sanofi, GSK variant-specific COVID shot found effective against Omicron © Reuters. FILE PHOTO: A logo on the Sanofi exhibition space at the Viva Technology conference dedicated to innovation and startups at Porte de Versailles exhibition center in Paris, France June 15, 2022. REUTERS/Benoit Tessier

By Natalie Grover

PARIS/LONDON (Reuters) - Late-stage data on an experimental COVID-19 vaccine from Sanofi (NASDAQ:SNY) and GSK has showed the shot confers protection against the Omicron variant of the virus, the companies said on Friday.

The so-called bivalent vaccine targets the Beta variant - first identified in South Africa - as well as the original Wuhan strain of the virus.

In a trial involving 13,000 adults, the vaccine demonstrated an efficacy rate of 64.7% against symptomatic COVID, and 72% efficacy against infections specifically caused by the Omicron variant.

When used in people who previously had COVID, the results were stronger. The vaccine generated an efficacy rate of 75.1% against symptomatic COVID and 93.2% in Omicron-confirmed symptomatic cases, the companies said.

"Sanofi-GSK’s vaccine is the first candidate to demonstrate efficacy in a placebo-controlled trial in an environment of high Omicron variant circulation," Sanofi said in a statement.

Sanofi's Paris-listed shares and GSK's London-listed shares were both up more than 1% in morning trading.

Earlier this month, the bivalent vaccine showed potential in two trials to protect against the virus' main variants of concern - the Omicron BA.1 and BA.2 strains - when used as a booster shot.

Sanofi and GSK, two of the world's biggest vaccine makers, are hoping to gain a foothold in the market for next-generation variant-focused COVID shots, after falling behind competitors including Moderna (NASDAQ:MRNA), AstraZeneca (NASDAQ:AZN) and Pfizer-BioNTech, in the original race to contain the pandemic.

The new data supporting the bivalent vaccine will be submitted to regulatory authorities with the hope of making the shot available later this year, the companies said on Friday.

Sanofi and GSK's original COVID vaccine is already under review by the European Medicines Agency.

The companies have bet that this bivalent vaccine moulded on the now-supplanted Beta variant will confer broad protection against future viral strains on the basis that Beta expresses similar mutations across multiple variants of concern, including Omicron.

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26-06-2022 17:42:05 (UTC+7)

EUR/USD

1.0554

+0.0031 (+0.29%)

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EUR/USD

1.0554

+0.0031 (+0.29%)

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GBP/USD

1.2272

+0.0012 (+0.10%)

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USD/JPY

135.23

+0.29 (+0.22%)

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AUD/USD

0.6944

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USD/CAD

1.2891

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EUR/JPY

142.71

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1.0114

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Gold Futures

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21.130

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US Coffee C Futures

223.40

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Euro Stoxx 50

3,533.17

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S&P 500

3,911.74

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DAX

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21,719.06

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US Small Cap 2000

1,765.74

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IBEX 35

8,244.10

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BASF SE NA O.N.

42.215

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Bayer AG NA

57.79

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181.20

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Adidas AG

170.36

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5.966

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Siemens AG Class N

102.62

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8.919

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 EUR/USD1.0554Buy
 GBP/USD1.2272↑ Sell
 USD/JPY135.23↑ Buy
 AUD/USD0.6944↑ Sell
 USD/CAD1.2891↑ Sell
 EUR/JPY142.71↑ Buy
 EUR/CHF1.0114↑ Sell
 Gold1,828.10↑ Buy
 Silver21.130Sell
 Copper3.7365Sell
 Crude Oil WTI107.06↑ Sell
 Brent Oil113.19↑ Sell
 Natural Gas6.173↑ Buy
 US Coffee C223.40↑ Buy
 Euro Stoxx 503,533.17Neutral
 S&P 5003,911.74↑ Buy
 DAX13,118.13↑ Sell
 FTSE 1007,208.81↑ Buy
 Hang Seng21,719.06↑ Buy
 Small Cap 20001,765.74↑ Buy
 IBEX 358,244.10Sell
 BASF42.215↑ Buy
 Bayer57.79↑ Sell
 Allianz181.20↑ Sell
 Adidas170.36↑ Sell
 Lufthansa5.966↑ Sell
 Siemens AG102.62↑ Buy
 Deutsche Bank AG8.919↑ Buy
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