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AstraZeneca says early trial data indicates third dose helps against Omicron

By Pushkala Aripaka and Ludwig Burger (Reuters) -AstraZeneca said on Thursday that preliminary data from a trial showed that its COVID-19 shot, Vaxzevria, generated an increase in...
AstraZeneca says early trial data indicates third dose helps against Omicron © Reuters. FILE PHOTO: A test tube labelled with the Vaccine is seen in front of AstraZeneca logo in this illustration taken, September 9, 2020. REUTERS/Dado Ruvic/Illustration

By Pushkala Aripaka and Ludwig Burger

(Reuters) -AstraZeneca said on Thursday that preliminary data from a trial showed that its COVID-19 shot, Vaxzevria, generated an increase in antibodies against the Omicron and other variants when given as a third booster dose.

The increased response, also against the Delta variant, was seen in a blood analysis of people who were previously vaccinated with either Vaxzevria or an mRNA vaccine, the drugmaker said, adding that it would submit this data to regulators worldwide given the urgent need https://www.reuters.com/business/healthcare-pharmaceuticals/why-you-should-still-try-avoid-catching-omicron-2022-01-12 for boosters.

AstraZeneca (NASDAQ:AZN) has developed the vaccine with researchers from the University of Oxford, and lab studies conducted by the university last month https://www.reuters.com/business/healthcare-pharmaceuticals/astrazeneca-shot-third-dose-works-against-omicron-study-2021-12-23 already found a three-dose course of Vaxzevria boosted antibody levels in the blood against the rapidly spreading Omicron variant.

The brief statement on Thursday, which did not include specific data, was the first by AstraZeneca on the protective potential of Vaxzevria as a booster shot following a two shot-course of either an mRNA based vaccine or Vaxzevria. Vaccines base on mRNA technology are made by BioNTech-Pfizer and Moderna (NASDAQ:MRNA).

The company said the findings "add to the growing body of evidence supporting Vaxzevria as a third dose booster irrespective of the primary vaccination schedules tested".

The data on Vaxzevria's potential as a booster came from a comparative analysis in a trial testing a redesigned vaccine which uses the vector technology behind Vaxzevria but targeting the now-superseded Beta variant. AstraZeneca is trying to show the Beta-specific vaccine has potential also against other variants and more trial data is expected during the first half of the year.

Separately, Oxford University and AstraZeneca last month started work on a vaccine specifically targeting Omicron though Astra - as well as other vaccine makers in similar development projects - have said it was not yet clear whether such an upgrade was needed.

A major British trial in December found that AstraZeneca's shot increased antibodies when given as a booster after initial vaccination with its own shot or Pfizer (NYSE:PFE)'s, but that was before the explosive spread of the Omicron variant.

However, the study at the time concluded that mRNA vaccines made by Pfizer and Moderna gave a biggest boost to antibodies when given as a third dose.

AstraZeneca and its contract manufacturing partners have supplied over 2.5 billion doses globally of its vaccine, even though it is not approved in the United States, while BioNTech-Pfizer have shipped about 2.6 billion doses.

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24-01-2022 05:08:03 (UTC+7)

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 EUR/USD1.1326Neutral
 GBP/USD1.3522↑ Sell
 USD/JPY113.60↑ Buy
 AUD/USD0.7149↑ Sell
 USD/CAD1.2606↑ Buy
 EUR/JPY128.66↑ Buy
 EUR/CHF1.0326Sell
 Gold1,840.40↑ Sell
 Silver24.215↑ Sell
 Copper4.4618↑ Sell
 Crude Oil WTI85.32↑ Sell
 Brent Oil87.30↑ Sell
 Natural Gas3.736↑ Sell
 US Coffee C235.88↑ Sell
 Euro Stoxx 504,154.85↑ Sell
 S&P 5004,397.93↑ Sell
 DAX15,375.59↑ Sell
 FTSE 1007,428.11↑ Sell
 Hang Seng24,656.46↑ Buy
 Small Cap 20001,987.92Buy
 IBEX 358,568.42↑ Sell
 BASF65.320↑ Buy
 Bayer51.03↑ Sell
 Allianz220.25↑ Buy
 Adidas246.35Sell
 Lufthansa6.739↑ Sell
 Siemens AG142.52↑ Buy
 Deutsche Bank AG11.156↑ Buy
Mua/Bán 1 chỉ SJC
# So hôm qua # Chênh TG
SJC Eximbank6,170/ 6,210
(50/ 50) # 1,153
SJC HCM6,150/ 6,210
(27/ 17) # 1,153
SJC Hanoi6,150/ 6,212
(27/ 17) # 1,155
SJC Danang6,150/ 6,212
(27/ 17) # 1,155
SJC Nhatrang6,150/ 6,212
(27/ 17) # 1,155
SJC Cantho6,150/ 6,212
(27/ 17) # 1,155
Cập nhật 24-01-2022 05:08:08
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EUR25.000,4426.401,93
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KRW16,4019,98
Cập nhật lúc 17:03:13 24/01/2022
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